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Saturday, February 23, 2008

Aging Slows With Vitamin D

Vitamin D may help slow ageing

A vitamin made when sunlight hits the skin could help slow down the ageing of cells and tissues, say researchers.
A King's College London study of more than 2,000 women found those with higher vitamin D levels showed fewer ageing-related changes in their DNA.

However, the American Journal of Clinical Nutrition study stops short of proving cause and effect.

A lack of vitamin D, also found in some foods, has also been linked to multiple sclerosis and rheumatoid arthritis.


The genetic material inside every cell has an inbuilt "clock", which counts down every time the cell reproduces itself.

The shortening of these strands of DNA called telomeres is one way of examining the ageing process at a cellular level.

Snapshot measurement

The King's team looked at white blood cells, which tend to experience faster rates of turnover - and faster shortening of telomeres - when the body's tissues are suffering more inflammation.

They looked at a total of 2,160 women aged between 18 and 79, and took a snapshot measurement of the levels of vitamin D in their bloodstream, comparing this to the length of the telomeres in their white blood cells.

They found that, after adjusting the results for the age of the volunteer, women with higher levels of vitamin D were more likely to have longer telomeres in these cells, and vice versa.


Professor Brent Richards, who led the study, said: "These results are exciting because they demonstrate for the first time that people who have higher levels of vitamin D may age more slowly than people with lower levels of vitamin D.

"This could help to explain how vitamin D has a protective effect on many ageing-related diseases, such as heart disease and cancer."

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